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Reduction of 1-sec-Butyl-2-nitrobenzene using Sn/HCl

Abstract: We review the Sn/HCl reduction of 1-sec-butyl-2-nitrobenzene (ortho-nitro-sec-butylbenzene) to its corresponding amine. Emphasis is on literature-reported procedures, detailing reagent ratios, temperature control, reaction time, work-up, and yields. This amine is a monomer precursor for poly(2-sec-butylaniline), offering enhanced solubility in…